S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Group	Environmental Condition	Log2FC
Gln3p	YDL215C	PubMed Coschigano PW et al., Molecular and cellular biology, 1991 Feb;11(2):822-32	Indirect	Enzyme activity - wt vs TF mutant	Positive	S288c	Nitrogen source quality/availability	Glutamine - Yeast cells were grown with glutamine as a nitrogen source	N/A
		PubMed Deckert J et al., Molecular and cellular biology, 1995 Nov;15(11):6109-17	Indirect	lacZ - wt vs TF mutant	Positive	S288c	Nitrogen source quality/availability	cells grown on glutamine as nitrogen source	N/A
		PubMed Kuras L et al., FEBS letters, 1995 Jun 19;367(1):15-8	N/A		N/A	S288c	N/A	N/A	N/A
		PubMed Hagen DC et al., Molecular and cellular biology, 1993 Nov;13(11):6866-75	Indirect	Northern blot - wt vs TF mutant	Positive	SIGMA1278b	Nitrogen source quality/availability	Wickerham's minimal medium + proline	N/A
		PubMed Cunningham TS et al., Journal of bacteriology, 1996 Jun;178(12):3470-9	Direct	EMSA	N/A	S288c	In vitro	in vitro	N/A
		PubMed Shamji AF et al., Current biology : CB, 2000 Dec 14-28;10(24):1574-81	Indirect	Microarray analysis - wt vs TF mutant	Positive	S288c	Nitrogen source quality/availability	30 min 50 nM treatment with rapamycin in YPD	N/A
		PubMed Harbison CT et al., Nature, 2004 Sep 2;431(7004):99-104	Direct	Chip-on-chip	N/A	S288c	N/A	N/A	N/A
		PubMed Hernández H et al., Biochemical and biophysical research communications, 2011 Jan 21;404(3):859-64	Direct	ChIP	N/A	S288c	Nitrogen source quality/availability	3-aminotriazole	N/A
		PubMed Georis I et al., The Journal of biological chemistry, 2011 Dec 30;286(52):44897-912	Indirect	RT-PCR - wt vs TF mutant	Positive	S288c	Nitrogen source quality/availability	Methionine sulfoximine	N/A
		PubMed Rai R et al., Genetics, 2015 Nov;201(3):989-1016	Indirect	RT-PCR - wt vs TF mutant	Positive	S288c	Nitrogen source quality/availability	gln3DELTAgat1DELTA cells were grown in YNB-proline medium with Gln31 â€“730-Myc13 or with Gln3L332D,L336D,M340D,L343D-Myc13	N/A
		PubMed Ponomarova O et al., Cell systems, 2017 Oct 25;5(4):345-357.e6	Indirect	RNA-seq analysis - WT vs TF Deletion	Positive	S90	Cell cycle/morphology	Second acidic phase (day 21): Giant colonies grown on GM solid agar (1% yeast extract, 3% glycerol, 2% agar, 30 mM CaCl2) at room temperature; colonies harvested at day 21, corresponding to the second acidic phase.	1.2887463707363
			Indirect	RNA-seq analysis - WT vs TF Deletion	Positive	S90	Unstressed log-phase growth (control)	Grown in CDM35 at 30 ºC and harvested at OD600 of 1. Transcription factor gene deletion.	1.2887463707363
		PubMed Branco J et al., Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2022 Dec;28(12):1655.e5-1655.e8	Indirect	RT-PCR - wt vs TF mutant	Positive	BY4741	Nitrogen source quality/availability	YPD medium + Rap + 6h during whole-cell bioconversion	N/A
		PubMed Georis I et al., Yeast (Chichester, England), 2024 Apr;41(4):207-221	Indirect	RT-PCR - wt vs TF mutant	Positive	S288C	Nitrogen source quality/availability	YNB medium + L-Methionine sulfoximine	N/A
			Indirect	RT-PCR - wt vs TF mutant	Positive	S288C	Nitrogen source quality/availability	YNB medium - proline as sole nitrogen source	N/A
		PubMed Hurieva B et al., Nucleic acids research, 2024 Aug 27;52(15):8763-8777	Direct	ChEC-seq - wt vs TF truncations	N/A	BY4741	Unstressed log-phase growth (control)	SD medium	N/A