S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Group	Environmental Condition	Log2FC
Rap1p	YDL220C	PubMed Chua G et al., Proceedings of the National Academy of Sciences of the United States of America, 2006 Aug 8;103(32):12045-50	Indirect	Microarray analysis - wt vs TF overexpression	Negative	N/A	Carbon source quality/availability	Cells grown in selective medium supplemented with 2% raffinose before induction with 2% galactose for 3 h	N/A
		PubMed Alenquer M et al., FEMS yeast research, 2006 Dec;6(8):1130-9	Indirect	Microarray analysis - WT vs TF Deletion	Positive	W303a	Unstressed log-phase growth (control)	Grown in complete synthetic medium (CSM) when selection was required, or in rich medium (YPD) at 30°C. Temperature shift experiment: exponentially growing yeast cells grown in YPD (A600 = 0.8 − 1.2) at 37°C for 1 h. Transcription factor gene deletion.	1.132686
		PubMed Lickwar CR et al., Nature, 2012 Apr 11;484(7393):251-5	Direct	ChIP	N/A	S288c	Cell cycle/morphology	Cells arrested at G1 phase with alpha-factor cultivated in 2% Galactose YP medium	N/A
		PubMed Byun JY et al., Microbial cell factories, 2025 Feb 24;24(1):47	Indirect	RNA-seq - wt vs TF overexpression	Negative	CEN.PK2-1D	Unstressed log-phase growth (control)	YPD medium (9h) control	-1.01389083619809
			Indirect	RNA-seq analysis - TF Over-expression vs WT	Negative	cen.pk-2-1C	Unstressed log-phase growth (control)	RNA extraction at 9h. Medium: YPD (1% yeast extract, 2% peptone, 2% glucose) or synthetic complete (SC) medium supplemented as required for auxotrophic markers. Temperature: 30°C, aerobic shaking. Growth phase: exponential or stationary phase.	-2.01934979211675