S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Group	Environmental Condition	Log2FC
Yrr1p	YDR011W	PubMed Cui Z et al., Molecular microbiology, 1998 Sep;29(5):1307-15	Indirect	Northern blot - wt vs TF mutant	Positive	S288c	Unstressed log-phase growth (control)	YPD medium; mid-log phase	N/A
		PubMed Le Crom S et al., Molecular and cellular biology, 2002 Apr;22(8):2642-9	Indirect	Microarray analysis - wt vs TF mutant	Positive	S288c	Unstressed log-phase growth (control)	Yrr1-GAD chimera cells were cultivated in the presence of 2% galactose to induce protein expression	N/A
		PubMed Akache B et al., The Journal of biological chemistry, 2002 Jun 14;277(24):21254-60	Indirect	Northern blot - wt vs TF mutant	Positive	S288c	Unstressed log-phase growth (control)	Exponential-phase cells cultivated in SC medium	N/A
		PubMed Lucau-Danila A et al., The Journal of biological chemistry, 2003 Dec 26;278(52):52641-50	Indirect	Microarray analysis - wt vs TF mutant	Positive	BY4742	Unstressed log-phase growth (control)	Minimal synthetic medium; early-log phase; Galactose induction; YRR1-GAD is chimeric protein	N/A
		PubMed Onda M et al., Gene, 2004 May 12;332():51-9	Indirect	Microarray analysis - wt vs TF mutant	Positive	S288c	Unstressed log-phase growth (control)	YPGal + Adenine	N/A
		PubMed Reimand J et al., Nucleic acids research, 2010 Aug;38(14):4768-77	Indirect	Microarray analysis - WT vs TF Deletion	Positive	BY4741; S288C; R1158	Unstressed log-phase growth (control)	Standard YPD conditions Dataset ewxtracted from The Longhorn Array Database (LAD). Transcription factor gene deletion.	0.22562977503918
		PubMed Kodo N et al., Biochemical and biophysical research communications, 2013 Apr 26;434(1):42-7	Indirect	RT-PCR - wt vs TF mutant	Positive	S288c	Unstressed log-phase growth (control)	SD medium	N/A
		PubMed Gallagher JE et al., Genes & development, 2014 Feb 15;28(4):409-21	Direct	ChIP-seq	N/A	S288c	Carbon source quality/availability	YPGlycerol medium	N/A
		PubMed Wang X et al., Frontiers in microbiology, 2017;8():367	Indirect	RNA-seq analysis - WT vs TF Deletion	Positive	BY4741	Unstressed log-phase growth (control)	Cells harvested from 300 ml of culture (specific medium not clear) at an OD600 of 0.4. Transcription factor gene overexpression pAFT2-1up vs aft2Δ strain.	1.4789507095884
			Indirect	RNA-seq analysis - WT vs TF Deletion	Positive	BY4741	Stress	Grown in SD medium until log phase (OD600 ≈ 1.6-2.0) at 30 ºC, in the presence of 5 mM vanillin (inhibitor). Transcription factor gene deletion.	1.4789507095884
		PubMed Rong-Mullins X et al., G3 (Bethesda, Md.), 2018 Feb 2;8(2):607-619	Indirect	RNA-seq - wt vs TF mutant	Negative	S96	Stress	YPD medium with 0.25 microg/ml 4NQO	N/A
		PubMed Rossi MJ et al., Nature, 2021 Apr;592(7853):309-314	Direct	ChIP-exo	N/A	BY4741	Unstressed log-phase growth (control)	YPD medium, 25.C	N/A
		PubMed Zhao W et al., Microbial cell factories, 2023 Mar 11;22(1):48	Indirect	RT-PCR - wt vs TF mutant	Positive	BY4741	Stress	SC medium + vanillin stress	N/A
			Indirect	RT-PCR - wt vs TF overexpression	Positive	BY4741	Unstressed log-phase growth (control)	SC medium	N/A
			Indirect	RT-PCR - wt vs TF overexpression	Positive	BY4741	Stress	SC medium + vanillin stress	N/A
			Indirect	RT-PCR - wt vs TF variant overexpression	Positive	BY4741	Stress	SC medium + vanillin stress	N/A