S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Group	Environmental Condition	Log2FC
Rph1p	YDR500C	PubMed Schroeder EA et al., Cell metabolism, 2013 Jun 4;17(6):954-964	Indirect	Microarray analysis - WT vs TF Deletion	Negative	DBY2006	Stress	2h men: Cultures grown in minimal dextrose medium supplemented with essential amino acids at 30°C, 200 rpm. Cells treated with 50 µM menadione during exponential growth (OD600 0.5 to 2.0). RNA harvested at 2 h (exponential phase).	-0.722372
		PubMed Shu WJ et al., Nucleic acids research, 2020 Sep 4;48(15):8360-8373	Indirect	RNA-seq analysis - WT vs TF Deletion	Positive	BY4741	Carbon source quality/availability	Steady state carbon-limited chemostat cultures operated at a dilution rate of 0.05 per h by continuous addition of medium (feed concentration of glucose, 10 g/liter) at 30°C. pH controlled at 5, aerated with 0.5 volume of air/volume of liquid/min and with 800 rpm agitation. Transcription factor gene deletion.	0.368174058662389
			Indirect	RNA-seq analysis - WT vs TF Deletion	Negative	BY4741	Carbon source quality/availability	Ethanol medium - Overexpression media lacked leucine to ensure plasmid selection. The cultures grown for 70 h in ethanol medium were diluted twice with a fresh medium to ensure continuous growth.	-0.380948083736213
			Indirect	RNA-seq analysis - WT vs TF Deletion	Positive	BY4741	Unstressed log-phase growth (control)	Grown in YPD to OD600 of 0.8 at 30 ºC. Transcription factor gene deletion.	0.368174058662389
			Indirect	RNA-seq analysis - WT vs TF Deletion	Negative	BY4741	Nitrogen source quality/availability	Grown in YPD to OD600 of 0.8 at 30 ºC. Treated with rapamycin for 2h (100 nM). Transcription factor gene deletion.	-0.380948083736213
		PubMed Fang W et al., Cell reports, 2022 Apr 12;39(2):110672	Indirect	RNA-seq analysis - WT vs TF Deletion	Positive	CEN.PK	Carbon source quality/availability	Yeast cells grown to log phase in YPL medium from 0.1 OD with switch to SL minimal medium for 3h. Transcription factor gene deletion.	0.398683659906505