S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Group	Environmental Condition	Log2FC
Ixr1p	YER070W	PubMed Workman CT et al., Science (New York, N.Y.), 2006 May 19;312(5776):1054-9	Direct	Chip-on-chip	N/A	S288c	N/A	N/A	N/A
		PubMed Reimand J et al., Nucleic acids research, 2010 Aug;38(14):4768-77	Indirect	Microarray analysis - WT vs TF Deletion	Positive	BY4741; S288C; R1158	Unstressed log-phase growth (control)	Standard YPD conditions Dataset ewxtracted from The Longhorn Array Database (LAD). Transcription factor gene deletion.	0.50666028926039
		PubMed Tsaponina O et al., PLoS genetics, 2011 May;7(5):e1002061	Direct	ChIP	N/A	S288c	Stress	exposure to 4-NQO	N/A
		PubMed Vizoso-Vázquez A et al., Applied microbiology and biotechnology, 2012 Apr;94(1):173-84	Indirect	Microarray analysis - WT vs TF Deletion	Negative	BY4741	Oxygen availability	Grown in SC medium with defined amino acid supplements and 2% glucose at 30 °C, in Erlenmeyer flasks filled to 40% volume and shaken at 250 rpm. Cells shifted from aerobic to hypoxic conditions at OD600 0.8 by nitrogen bubbling for 3 hours. Transcription factor gene deletion in hypoxic condition.	N/A
		PubMed Krakowiak J et al., eLife, 2018 Feb 2;7():	Indirect	Microarray analysis - WT vs TF Deletion	Positive	W303a	Unstressed log-phase growth (control)	Grown overnight in complete SD medium with specific amino acid supplements and 2% glucose, then diluted to OD600 0.4 in fresh medium and cultured at 30 °C with shaking until mid-log phase (OD600 0.6). Transcription factor gene deletion.	0.84031
		PubMed Krakowiak J et al., eLife, 2018 Feb 2;7():	Indirect	Microarray analysis - WT vs TF Deletion	Positive	W303a	Stress	Grown overnight in complete SD medium with specific amino acid supplements and 2% glucose, then diluted to OD600 0.4 in fresh medium and cultured at 30 °C with shaking until mid-log phase (OD600 0.6). Cisplatin treatment (600 μM in DMSO), incubated for 4 hours at 30 °C in the dark with agitation. Transcription factor gene deletion.	0.93407