S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Group	Environmental Condition	Log2FC
Met4p	YGR087C	PubMed Thorsen M et al., Physiological genomics, 2007 Jun 19;30(1):35-43	Indirect	Microarray analysis - WT vs TF Deletion	Positive	W303-1A	Stress	Grown in minimal YNB medium (0.67% yeast nitrogen base) supplemented with auxotrophic requirements and 2% glucose at 30°C. Exponentially growing cells exposed to 0.2 mM sodium arsenite. Transcription factor gene deletion.	0.447
		PubMed Cormier L et al., Nucleic acids research, 2010 Aug;38(15):4998-5014	Direct	ChIP	N/A	W303	Stress	Isogenic strain expressing Myc-tagged Met4 was grown to early log phase in YPD medium and exposed to 0.5 mM Cd2+. Binding to PDC6 upstream region (from -455 to -306 relative to ATG)	N/A
			Direct	ChIP	N/A	W303	Stress	Isogenic strain expressing Myc-tagged version of Met4 was grown to early log phase in YPD medium and exposed to 0.5mM Cd2+.	N/A
			Indirect	RT-PCR - wt vs TF mutant	Positive	W303	Carbon source quality/availability	Met4 hyperactivation: met4::GAL1-MET4 DELTAmet30 cells were grown in YP-raffinose medium to early logphase and supplemented or not with galactose	N/A
			Indirect	RT-PCR - wt vs TF mutant	Positive	W303	Stress	wt vs DELTAmet4: cells were grown to early log phase in YPD medium and exposed to 0.5 mM Cd2+	N/A