S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Group	Environmental Condition	Log2FC
Ixr1p	YHR096C	PubMed Lee TI et al., Science (New York, N.Y.), 2002 Oct 25;298(5594):799-804	Direct	Chip-on-chip	N/A	S288c	Unstressed log-phase growth (control)	YPD medium; mid-log phase	N/A
		PubMed Workman CT et al., Science (New York, N.Y.), 2006 May 19;312(5776):1054-9	Direct	Chip-on-chip	N/A	S288c	N/A	N/A	N/A
		PubMed Reimand J et al., Nucleic acids research, 2010 Aug;38(14):4768-77	Indirect	Microarray analysis - WT vs TF Deletion	Positive	BY4741; S288C; R1158	Unstressed log-phase growth (control)	Standard YPD conditions Dataset ewxtracted from The Longhorn Array Database (LAD). Transcription factor gene deletion.	0.35588538937037
		PubMed Vizoso-Vázquez A et al., Applied microbiology and biotechnology, 2012 Apr;94(1):173-84	Indirect	Microarray analysis - wt vs TF mutant	Negative	S288c	Oxygen availability	Hypoxia	N/A
		PubMed Krakowiak J et al., eLife, 2018 Feb 2;7():	Indirect	Microarray analysis - WT vs TF Deletion	Positive	W303a	Unstressed log-phase growth (control)	Grown overnight in complete SD medium with specific amino acid supplements and 2% glucose, then diluted to OD600 0.4 in fresh medium and cultured at 30 °C with shaking until mid-log phase (OD600 0.6). Transcription factor gene deletion.	0.65357667
		PubMed Krakowiak J et al., eLife, 2018 Feb 2;7():	Indirect	Microarray analysis - WT vs TF Deletion	Positive	W303a	Stress	Grown overnight in complete SD medium with specific amino acid supplements and 2% glucose, then diluted to OD600 0.4 in fresh medium and cultured at 30 °C with shaking until mid-log phase (OD600 0.6). Cisplatin treatment (600 μM in DMSO), incubated for 4 hours at 30 °C in the dark with agitation. Transcription factor gene deletion.	0.55235