Yeastract
YEASTRACT+ INESC-ID IST IBB
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Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.
Transcription
Factor
Target
ORF/Genes
References Evidence
Code
Evidence
Experiment
Association
Type
Strain Environmental
Group
Environmental
Condition
Log2FC
Rap1p YHR174W PubMed external link Brindle PK et al., Molecular and cellular biology, 1990 Sep;10(9):4872-85Brindle PK et al., Molecular and cellular biology, 1990 Sep;10(9):4872-85 Direct EMSA N/A S288c In vitro in vitro N/A
PubMed external link Willett CE et al., Molecular and cellular biology, 1993 Apr;13(4):2623-33Willett CE et al., Molecular and cellular biology, 1993 Apr;13(4):2623-33 Direct EMSA N/A S288c In vitro in vitro N/A
PubMed external link Reimand J et al., Nucleic acids research, 2010 Aug;38(14):4768-77Reimand J et al., Nucleic acids research, 2010 Aug;38(14):4768-77 Indirect Microarray analysis - WT vs TF Deletion Positive BY4741; S288C; R1158 Unstressed log-phase growth (control) Standard YPD conditions Dataset ewxtracted from The Longhorn Array Database (LAD). Transcription factor gene deletion. 1.8321979883968
PubMed external link Buechel ER et al., FEBS letters, 2024 Jan;598(2):169-186Buechel ER et al., FEBS letters, 2024 Jan;598(2):169-186 Direct ChEC-seq2 N/A BY4741 Unstressed log-phase growth (control) Control N/A
PubMed external link Byun JY et al., Microbial cell factories, 2025 Feb 24;24(1):47Byun JY et al., Microbial cell factories, 2025 Feb 24;24(1):47 Indirect RNA-seq - wt vs TF overexpression Positive CEN.PK2-1D Carbon source quality/availability YPD medium (15h) (diauxic shift) 2.1072454549641
Indirect RNA-seq analysis - TF Over-expression vs WT Positive cen.pk-2-1C Unstressed log-phase growth (control) RNA extraction at 15h. Medium: YPD (1% yeast extract, 2% peptone, 2% glucose) or synthetic complete (SC) medium supplemented as required for auxotrophic markers. Temperature: 30°C, aerobic shaking. Growth phase: exponential or stationary phase. 4.30867850553536