S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Group	Environmental Condition	Log2FC
Yrr1p	YKL217W	PubMed Le Crom S et al., Molecular and cellular biology, 2002 Apr;22(8):2642-9	Indirect	Microarray analysis - TF GOF vs WT	Negative	SEY6210	Unstressed log-phase growth (control)	100 ml of cell culture grown to OD600nm (600 nm) of 1.5.	-0.39975861
		PubMed Chua G et al., Proceedings of the National Academy of Sciences of the United States of America, 2006 Aug 8;103(32):12045-50	Indirect	Microarray analysis - wt vs TF overexpression	Positive	N/A	Carbon source quality/availability	Cells grown in selective medium supplemented with 2% raffinose before induction with 2% galactose for 3 h	N/A
		PubMed Wang X et al., Frontiers in microbiology, 2017;8():367	Indirect	RNA-seq analysis - WT vs TF Deletion	Positive	BY4741	Unstressed log-phase growth (control)	Cells harvested from 300 ml of culture (specific medium not clear) at an OD600 of 0.4. Transcription factor gene overexpression pAFT2-1up vs aft2Δ strain.	0.705829586268802
			Indirect	RNA-seq analysis - WT vs TF Deletion	Positive	BY4741	Stress	Grown in SD medium until log phase (OD600 ≈ 1.6-2.0) at 30 ºC, in the presence of 5 mM vanillin (inhibitor). Transcription factor gene deletion.	0.705829586268802
		PubMed Rong-Mullins X et al., G3 (Bethesda, Md.), 2018 Feb 2;8(2):607-619	Indirect	RNA-seq - wt vs TF mutant	Negative	S96	Unstressed log-phase growth (control)	YPD	N/A
			Indirect	RNA-seq - wt vs TF mutant	Positive	S96	Stress	YPD medium with 0.25 microg/ml 4NQO	N/A