S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Group	Environmental Condition	Log2FC
Met4p	YLR303W	PubMed O'Connell KF et al., Molecular and cellular biology, 1995 Apr;15(4):1879-88	Indirect	Northern blot - wt vs TF mutant	Positive	S288c	Nitrogen source quality/availability	Yeast cells were pregrown in 1.0 mM methionine-containing medium before being shifted into medium lacking methionine or, as the control, back into fresh methionine-containing medium.	N/A
		PubMed Kuras L et al., The EMBO journal, 1997 May 1;16(9):2441-51	Indirect	lacZ - wt vs TF mutant	Positive	S288c	Nitrogen source quality/availability	B medium 0,05mM methionine	N/A
		PubMed Kaiser P et al., Cell, 2000 Aug 4;102(3):303-14	Direct	ChIP	N/A	S288c	N/A	N/A	N/A
		PubMed Aranda A et al., Applied and environmental microbiology, 2004 Apr;70(4):1913-22	Indirect	Western blot - wt vs TF mutant	Positive	S288c	Stress	1 g/L acetaldehyde (1H)	N/A
			Indirect	Western blot - wt vs TF mutant	Positive	S288c	Unstressed log-phase growth (control)	log-phase growth; 2 % glucose YPD	N/A
		PubMed Barbey R et al., The EMBO journal, 2005 Feb 9;24(3):521-32	Indirect	Northern blot - wt vs TF mutant	Positive	S288c	Stress	Rich YPD Medium + 0,5mM Cadmium	N/A
		PubMed Thorsen M et al., Physiological genomics, 2007 Jun 19;30(1):35-43	Indirect	Northern blot - wt vs TF mutant	Positive	W303-1A	Stress	0.2 mM As(III), 1 h	N/A
			Indirect	Microarray analysis - WT vs TF Deletion	Positive	W303-1A	Stress	Grown in minimal YNB medium (0.67% yeast nitrogen base) supplemented with auxotrophic requirements and 2% glucose at 30°C. Exponentially growing cells exposed to 0.2 mM sodium arsenite. Transcription factor gene deletion.	2.367
		PubMed Archer CT et al., Nucleic acids research, 2010 Jan;38(3):789-96	Indirect	Microarray analysis - wt vs TF mutant	Positive	W303	Unstressed log-phase growth (control)	minimal B-media + 0.5 mM methionine	N/A
		PubMed Cormier L et al., Nucleic acids research, 2010 Aug;38(15):4998-5014	Direct	ChIP	N/A	W303	Stress	Isogenic strain expressing Myc-tagged version of Met4 was grown to early log phase in YPD medium and exposed to 0.5mM Cd2+.	N/A
		PubMed Tyrrell A et al., Proceedings of the National Academy of Sciences of the United States of America, 2010 Nov 16;107(46):19796-801	Indirect	RT-PCR - wt vs TF mutant	Positive	S288c	Nitrogen source quality/availability	methionine depletion	N/A
		PubMed Hickman MJ et al., Molecular biology of the cell, 2011 Nov;22(21):4192-204	Indirect	Microarray analysis - wt vs TF mutant	Positive	S288c	Unstressed log-phase growth (control)	YPD medium; mid-log phase	N/A
		PubMed McIsaac RS et al., Molecular biology of the cell, 2011 Nov;22(22):4447-59	Indirect	Microarray analysis - wt vs TF mutant	Positive	S288c	Stress	pulse of beta-estradiol	N/A
		PubMed Ndoja A et al., Molecular cell, 2014 Mar 20;53(6):893-903	Direct	ChIP	N/A	S288c	Unstressed log-phase growth (control)	3xHA-tagged Met4 or Met4(K163R) were expressed from the GAL promoter with Myc-tagged at the endogenous CDC48 locus for 40 min and then cells were fixed for ChIP analysis.	N/A