S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Group	Environmental Condition	Log2FC
Yrr1p	YMR102C	PubMed Le Crom S et al., Molecular and cellular biology, 2002 Apr;22(8):2642-9	Indirect	Microarray analysis - wt vs TF mutant	Positive	S288c	Unstressed log-phase growth (control)	Yrr1-GAD chimera cells were cultivated in the presence of 2% galactose to induce protein expression	N/A
		PubMed Lucau-Danila A et al., The Journal of biological chemistry, 2003 Dec 26;278(52):52641-50	Indirect	Microarray analysis - wt vs TF mutant	Positive	BY4742	Unstressed log-phase growth (control)	Minimal synthetic medium; early-log phase; Galactose induction; YRR1-GAD is chimeric protein	N/A
		PubMed Gallagher JE et al., Genes & development, 2014 Feb 15;28(4):409-21	Direct	ChIP-seq	N/A	S288c	Carbon source quality/availability	YPGlycerol medium	N/A
		PubMed Wang X et al., Frontiers in microbiology, 2017;8():367	Indirect	RNA-seq analysis - WT vs TF Deletion	Negative	BY4741	Unstressed log-phase growth (control)	Cells harvested from 300 ml of culture (specific medium not clear) at an OD600 of 0.4. Transcription factor gene overexpression pAFT2-1up vs aft2Δ strain.	-0.717833951561832
			Indirect	RNA-seq analysis - WT vs TF Deletion	Negative	BY4741	Stress	Grown in SD medium until log phase (OD600 ≈ 1.6-2.0) at 30 ºC, in the presence of 5 mM vanillin (inhibitor). Transcription factor gene deletion.	-0.717833951561832
		PubMed Rong-Mullins X et al., G3 (Bethesda, Md.), 2018 Feb 2;8(2):607-619	Indirect	RNA-seq (Yrr1 mutant (I775E) vs Yrr1 mutant (I775T))	Negative	S96	Unstressed log-phase growth (control)	YPD	N/A
			Indirect	RNA-seq - wt vs TF mutant	Positive	S96	Unstressed log-phase growth (control)	YPD	N/A