Yeastract
YEASTRACT+ INESC-ID IST IBB
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Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.
Transcription
Factor		 Target
ORF/Genes		 References Evidence
Code		 Evidence
Experiment		 Association
Type		 Strain Environmental
Group		 Environmental
Condition		 Log2FC
Rap1p YNL067W PubMed external link Lieb JD et al., Nature genetics, 2001 Aug;28(4):327-34Lieb JD et al., Nature genetics, 2001 Aug;28(4):327-34 Direct Chip-on-chip N/A S288c N/A N/A N/A
PubMed external link Chua G et al., Proceedings of the National Academy of Sciences of the United States of America, 2006 Aug 8;103(32):12045-50Chua G et al., Proceedings of the National Academy of Sciences of the United States of America, 2006 Aug 8;103(32):12045-50 Indirect Microarray analysis - wt vs TF overexpression Negative N/A Carbon source quality/availability Cells grown in selective medium supplemented with 2% raffinose before induction with 2% galactose for 3 h N/A
PubMed external link Alenquer M et al., FEMS yeast research, 2006 Dec;6(8):1130-9Alenquer M et al., FEMS yeast research, 2006 Dec;6(8):1130-9 Indirect Microarray analysis - WT vs TF Deletion Positive W303a Unstressed log-phase growth (control) Grown in complete synthetic medium (CSM) when selection was required, or in rich medium (YPD) at 30°C. Temperature shift experiment: exponentially growing yeast cells grown in YPD (A600 = 0.8 − 1.2) at 37°C for 1 h. Transcription factor gene deletion. 1.063842
PubMed external link Kasahara K et al., Molecular and cellular biology, 2007 Oct;27(19):6686-705Kasahara K et al., Molecular and cellular biology, 2007 Oct;27(19):6686-705 Direct Chip-on-chip N/A S288c Unstressed log-phase growth (control) YPD N/A
PubMed external link Badis G et al., Molecular cell, 2008 Dec 26;32(6):878-87Badis G et al., Molecular cell, 2008 Dec 26;32(6):878-87 Direct ChIP N/A S288c N/A N/A N/A
PubMed external link Reimand J et al., Nucleic acids research, 2010 Aug;38(14):4768-77Reimand J et al., Nucleic acids research, 2010 Aug;38(14):4768-77 Indirect Microarray analysis - WT vs TF Deletion Positive BY4741; S288C; R1158 Unstressed log-phase growth (control) Standard YPD conditions Dataset ewxtracted from The Longhorn Array Database (LAD). Transcription factor gene deletion. 2.4876113204266
PubMed external link Rossi MJ et al., Nature, 2021 Apr;592(7853):309-314Rossi MJ et al., Nature, 2021 Apr;592(7853):309-314 Direct ChIP-exo N/A BY4741 Unstressed log-phase growth (control) YPD medium, 25.C N/A
PubMed external link Bondra ER et al., Proceedings of the National Academy of Sciences of the United States of America, 2023 Oct 3;120(40):e2304343120Bondra ER et al., Proceedings of the National Academy of Sciences of the United States of America, 2023 Oct 3;120(40):e2304343120 Direct ChIP - seq N/A W303 Unstressed log-phase growth (control) YPD medium N/A
PubMed external link Buechel ER et al., FEBS letters, 2024 Jan;598(2):169-186Buechel ER et al., FEBS letters, 2024 Jan;598(2):169-186 Direct ChEC-seq2 N/A BY4741 Unstressed log-phase growth (control) Control N/A
PubMed external link Byun JY et al., Microbial cell factories, 2025 Feb 24;24(1):47Byun JY et al., Microbial cell factories, 2025 Feb 24;24(1):47 Indirect RNA-seq - wt vs TF overexpression Negative CEN.PK2-1D Carbon source quality/availability YPD medium (36h) (post-diauxic shift) -1.29046003208076
Indirect RNA-seq analysis - TF Over-expression vs WT Negative cen.pk-2-1C Carbon source quality/availability RNA extraction at 36h. Medium: YPD (1% yeast extract, 2% peptone, 2% glucose) or synthetic complete (SC) medium supplemented as required for auxotrophic markers. Temperature: 30°C, aerobic shaking. Growth phase: exponential or stationary phase. -2.44606040617637