S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Group	Environmental Condition	Log2FC
Swi4p	YNR009W	PubMed Iyer VR et al., Nature, 2001 Jan 25;409(6819):533-8	Direct	Chip-on-chip	N/A	S288c	N/A	N/A	N/A
		PubMed Workman CT et al., Science (New York, N.Y.), 2006 May 19;312(5776):1054-9	Direct	Chip-on-chip	N/A	S288c	N/A	N/A	N/A
		PubMed Chua G et al., Proceedings of the National Academy of Sciences of the United States of America, 2006 Aug 8;103(32):12045-50	Indirect	Microarray analysis - wt vs TF overexpression	Positive	N/A	Carbon source quality/availability	Cells grown in selective medium supplemented with 2% raffinose before induction with 2% galactose for 3 h	N/A
		PubMed Reimand J et al., Nucleic acids research, 2010 Aug;38(14):4768-77	Indirect	Microarray analysis - WT vs TF Deletion	Positive	BY4741; S288C; R1158	Unstressed log-phase growth (control)	Standard YPD conditions Dataset ewxtracted from The Longhorn Array Database (LAD). Transcription factor gene deletion.	0.49878354231631
		PubMed Hendler A et al., PLoS genetics, 2017 May;13(5):e1006778	Direct	ChIP	N/A	15Daub	Cell cycle/morphology	Alpha factor arrested culturesÂ	N/A
			Indirect	RNA-seq analysis - WT vs TF Deletion	Negative	15Daub	Unstressed log-phase growth (control)	Yeast strains were grown in rich medium at 30°C to an optical density at 600 nm (OD600) of 0.5.	-0.541163412786603
			Indirect	RNA-seq analysis - WT vs TF Deletion	Positive	15Daub	Unstressed log-phase growth (control)	Yeast growth media (yeast-peptone-dextrose [YPD], yeast-peptone-acetate, and synthetic complete) were of standard composition	0.918592672161893
			Indirect	RNA-seq analysis - WT vs TF Deletion	Negative	15Daub	Cell cycle/morphology	Cells were grown in 7 ml of SC over-night at 30°C. Cells were synchronized by alpha factor arrest and release and immediately collected. Transcription factor gene deletion.	-0.541163412786603
			Indirect	RNA-seq analysis - WT vs TF Deletion	Positive	15Daub	Cell cycle/morphology	Cells were grown in 7 ml of SC over-night at 30°C. Cells were synchronized by alpha factor arrest and release and after 30 minutes they were collected. Transcription factor gene deletion.	0.918592672161893
		PubMed Rossi MJ et al., Nature, 2021 Apr;592(7853):309-314	Direct	ChIP-exo	N/A	BY4741	Unstressed log-phase growth (control)	YPD medium, 25.C	N/A