S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Group	Environmental Condition	Log2FC
Swi4p	YPL057C	PubMed Iyer VR et al., Nature, 2001 Jan 25;409(6819):533-8	Direct	Chip-on-chip	N/A	S288c	Cell cycle/morphology	alpha-factor treated cells	N/A
		PubMed Iyer VR et al., Nature, 2001 Jan 25;409(6819):533-8	Direct	Chip-on-chip	N/A	S288c	Stress	benomyl stress	N/A
		PubMed Workman CT et al., Science (New York, N.Y.), 2006 May 19;312(5776):1054-9	Direct	Chip-on-chip	N/A	S288c	N/A	N/A	N/A
		PubMed Chua G et al., Proceedings of the National Academy of Sciences of the United States of America, 2006 Aug 8;103(32):12045-50	Indirect	Microarray analysis - wt vs TF mutant	Positive	N/A	Unstressed log-phase growth (control)	Cells grown in synthetic medium supplemented with 2% dextrose	N/A
		PubMed Hendler A et al., PLoS genetics, 2017 May;13(5):e1006778	Indirect	RNA-seq analysis - WT vs TF Deletion	Positive	15Daub	Unstressed log-phase growth (control)	Yeast growth media (yeast-peptone-dextrose [YPD], yeast-peptone-acetate, and synthetic complete) were of standard composition	0.889820011725807
			Indirect	RNA-seq analysis - WT vs TF Deletion	Positive	15Daub	Cell cycle/morphology	Cells were grown in 7 ml of SC over-night at 30°C. Cells were synchronized by alpha factor arrest and release and after 30 minutes they were collected. Transcription factor gene deletion.	0.889820011725807
		PubMed Matos GS et al., Biochimica et biophysica acta. Molecular and cell biology of lipids, 2021 Sep;1866(9):158983	Indirect	RT-PCR - wt vs. TF mutant	Positive	BY4741	Cell cycle/morphology	Cells were cultivated to exponential phase in YPD medium and G1 synchronized with alpha factor. Cells were then released in minimal medium (SD medium) and harvested after 30 min	N/A