S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Group	Environmental Condition	Log2FC
Gln3p	YPR035W	PubMed Coschigano PW et al., Molecular and cellular biology, 1991 Feb;11(2):822-32	Indirect	Enzyme activity - wt vs TF mutant	Positive	S288c	Nitrogen source quality/availability	Glutamate - Yeast cells were grown with glutamate as a nitrogen source	N/A
		PubMed Deckert J et al., Molecular and cellular biology, 1995 Nov;15(11):6109-17	Indirect	lacZ - wt vs TF mutant	Positive	S288c	Nitrogen source quality/availability	cells grown on urea as nitrogen source	N/A
		PubMed Kuras L et al., FEBS letters, 1995 Jun 19;367(1):15-8	N/A		N/A	S288c	N/A	N/A	N/A
		PubMed Cunningham TS et al., Journal of bacteriology, 1996 Jun;178(12):3470-9	Direct	EMSA	N/A	S288c	In vitro	in vitro	N/A
		PubMed Cox KH et al., Yeast (Chichester, England), 1999 Jun 15;15(8):703-13	Indirect	Microarray analysis - wt vs TF mutant	Negative	TCY1	Nitrogen source quality/availability	Wickerham's minimal medium with 0,6% glucose and 0,1% of proline	N/A
		PubMed Shamji AF et al., Current biology : CB, 2000 Dec 14-28;10(24):1574-81	Indirect	Microarray analysis - wt vs TF mutant	Positive	S288c	Nitrogen source quality/availability	30 min 50 nM treatment with rapamycin in YPD	N/A
		PubMed Lee TI et al., Science (New York, N.Y.), 2002 Oct 25;298(5594):799-804	Direct	Chip-on-chip	N/A	S288c	Unstressed log-phase growth (control)	YPD medium; mid-log phase	N/A
		PubMed Harbison CT et al., Nature, 2004 Sep 2;431(7004):99-104	Direct	Chip-on-chip	N/A	S288c	Unstressed log-phase growth (control)	SC medium; mid-log phase	N/A
		PubMed Staschke KA et al., The Journal of biological chemistry, 2010 May 28;285(22):16893-911	Indirect	Microarray analysis - WT vs TF Deletion	Positive	WY798	Nitrogen source quality/availability	Grown in synthetic medium (SD) (2% dextrose, 0.5% ammonium sulfate) + amino acids w/o histidine (SC medium). Cells treated for 1 h with 10 mM 3-AT. Transcription factor gene deletion.	0.13750352
			Indirect	Microarray analysis - WT vs TF Deletion	Positive	WY798	Unstressed log-phase growth (control)	Grown in synthetic medium (SD) (2% dextrose, 0.5% ammonium sulfate) + amino acids w/o histidine (SC medium). Transcription factor gene deletion.	0.76601979
		PubMed Reimand J et al., Nucleic acids research, 2010 Aug;38(14):4768-77	Indirect	Microarray analysis - WT vs TF Deletion	Positive	BY4741; S288C; R1158	Unstressed log-phase growth (control)	Standard YPD conditions Dataset ewxtracted from The Longhorn Array Database (LAD). Transcription factor gene deletion.	2.0071787393039
		PubMed Ponomarova O et al., Cell systems, 2017 Oct 25;5(4):345-357.e6	Indirect	RNA-seq analysis - WT vs TF Deletion	Positive	S90	Cell cycle/morphology	Second acidic phase (day 21): Giant colonies grown on GM solid agar (1% yeast extract, 3% glycerol, 2% agar, 30 mM CaCl2) at room temperature; colonies harvested at day 21, corresponding to the second acidic phase.	2.33281513557399
			Indirect	RNA-seq analysis - WT vs TF Deletion	Positive	S90	Unstressed log-phase growth (control)	Grown in CDM35 at 30 ºC and harvested at OD600 of 1. Transcription factor gene deletion.	2.33281513557399
		PubMed Rossi MJ et al., Nature, 2021 Apr;592(7853):309-314	Direct	ChIP-exo	N/A	BY4741	Unstressed log-phase growth (control)	YPD medium, 25.C	N/A
		PubMed Hurieva B et al., Nucleic acids research, 2024 Aug 27;52(15):8763-8777	Direct	ChEC-seq - wt vs TF truncations	N/A	BY4741	Unstressed log-phase growth (control)	SD medium	N/A