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manipulating TF expression
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Gene Ontology Information
Locus Info
Protein Info
GO Info
Orthologs
Protein Name
Sla1p
Description
Cytoskeletal protein binding protein; required for assembly of the cortical actin cytoskeleton; interacts with proteins regulating actin dynamics and proteins required for endocytosis; found in the nucleus and cell cortex; has 3 SH3 domains
GO Terms:
Biological Process
level 5:
endosomal transport
level 5:
actin cortical patch organization
level 6:
endocytosis
level 6:
actin cortical patch assembly
level 9:
negative regulation of Arp2/3 complex-mediated actin nucleation
GO Terms:
Molecular Function
level 3:
protein-macromolecule adaptor activity
level 4:
identical protein binding
level 4:
cytoskeletal protein binding
level 4:
cargo adaptor activity
level 5:
ubiquitin binding
level 5:
actin binding
GO Terms:
Cellular Component
level 3:
actin cytoskeleton-regulatory complex
level 3:
cytoplasm
level 3:
SLAC complex
level 3:
membrane
level 4:
actin cortical patch
level 4:
endosome
level 4:
plasma membrane
level 4:
cellular bud neck
level 4:
cell cortex
level 4:
mating projection tip
level 5:
nucleus
level 5:
cytoskeleton
level 5:
endosome membrane
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