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Gene Ontology Information

Protein Name Tyc1p
Description Inhibitor of the Anaphase-Promoting Complex/Cyclosome (APC/C); binds to APC/C and inhibits the activity of both APC/C(Cdc20) and APC/C(Cdh1); inhibits the binding of Cdc20 and Cdh1 to APC/C; overexpression results in increased sensitivity to microtubule poison; originally identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching; functional homolog of human MAD2L1BP (p31comet)
GO Terms:
Biological Process		 level 8: negative regulation of ubiquitin protein ligase activity external link
GO Terms:
Molecular Function		 level 4: anaphase-promoting complex binding external link
level 6: ubiquitin ligase inhibitor activity external link
GO Terms:
Cellular Component		 level 1: cellular_component external link
External source Open in SGD external link
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