S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Elo2p
Description	Fatty acid elongase, involved in sphingolipid biosynthesis; acts on fatty acids of up to 24 carbons in length; mutations have regulatory effects on 1,3-beta-glucan synthase, vacuolar ATPase, and the secretory pathway; ELO2 has a paralog, ELO1, that arose from the whole genome duplication; lethality of the elo2 elo3 double null mutation is functionally complemented by human ELOVL1 and weakly complemented by human ELOVL3 or ELOV7
GO Terms: Biological Process	level 4: lipid metabolic process level 5: fatty acid metabolic process level 5: vesicle-mediated transport level 6: sphingolipid biosynthetic process level 6: fatty acid biosynthetic process level 7: fatty acid elongation level 7: late endosome to vacuole transport via multivesicular body sorting pathway level 7: very long-chain fatty acid biosynthetic process level 8: fatty acid elongation, saturated fatty acid level 9: fatty acid elongation, monounsaturated fatty acid level 9: fatty acid elongation, polyunsaturated fatty acid
GO Terms: Molecular Function	level 3: transferase activity level 6: very-long-chain 3-ketoacyl-CoA synthase activity level 7: fatty acid elongase activity
GO Terms: Cellular Component	level 3: membrane level 4: endoplasmic reticulum level 4: integral component of membrane level 5: endoplasmic reticulum membrane level 6: integral component of endoplasmic reticulum membrane
External source	Open in SGD