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Gene Ontology Information

Protein Name Cdc50p
Description Endosomal protein that interacts with phospholipid flippase Drs2p; interaction with Cdc50p is essential for Drs2p catalytic activity; mutations affect cell polarity and polarized growth; similar to Lem3p; CDC50 has a paralog, YNR048W, that arose from the whole genome duplication
GO Terms:
Biological Process		 level 4: actin cortical patch localization external link
level 5: intracellular protein transport external link
level 6: retrograde transport, endosome to Golgi external link
level 6: phospholipid translocation external link
level 6: endocytosis external link
level 7: aminophospholipid translocation external link
GO Terms:
Molecular Function		 level 5: aminophospholipid flippase activity external link
GO Terms:
Cellular Component		 level 3: membrane external link
level 3: cytosol external link
level 4: integral component of membrane external link
level 4: endosome external link
level 4: endoplasmic reticulum external link
level 4: Golgi apparatus external link
level 4: plasma membrane external link
level 5: trans-Golgi network external link
level 5: Cdc50p-Drs2p complex external link
level 6: late endosome membrane external link
External source Open in SGD external link
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