S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Osh2p
Description	Member of an oxysterol-binding protein family with seven members; in S. cerevisiae, family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability; contains FFAT motif; interacts with ER anchor Scs2p at patches at the plasma membrane and at the nuclear envelope; regulated by sterol binding; OSH2 has a paralog, SWH1, that arose from the whole genome duplication
GO Terms: Biological Process	level 4: maintenance of cell polarity level 5: exocytosis level 5: lipid transport level 6: ER to Golgi ceramide transport level 6: endocytosis level 6: sterol transport level 6: intermembrane lipid transfer level 6: piecemeal microautophagy of the nucleus level 7: reticulophagy
GO Terms: Molecular Function	level 3: lipid binding level 4: sterol transporter activity level 5: sterol transfer activity level 5: sterol binding
GO Terms: Cellular Component	level 3: cell periphery level 3: perinuclear endoplasmic reticulum level 3: membrane level 3: cytosol level 4: intracellular membrane-bounded organelle level 4: nuclear envelope level 4: endoplasmic reticulum level 4: plasma membrane level 4: cellular bud neck level 5: endoplasmic reticulum membrane level 5: cortical endoplasmic reticulum
External source	Open in SGD