S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Mps1p
Description	Dual-specificity kinase; autophosphorylation required for function; required for spindle pole body (SPB) duplication and spindle checkpoint function; contributes to bi-orientation by promoting formation of force-generating kinetochore-microtubule attachments in meiosis I; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, kinetochore protein Cnn1p, and checkpoint protein Mad1p; substrate of APCC(Cdh1); similar to human Mps1p
GO Terms: Biological Process	level 3: chromosome segregation level 4: meiotic spindle assembly checkpoint signaling level 4: chromosome separation level 5: spindle pole body duplication level 5: sister chromatid biorientation level 5: MAPK cascade level 5: mitotic spindle assembly checkpoint signaling level 5: spindle assembly level 6: protein phosphorylation level 6: phosphorylation level 7: peptidyl-tyrosine phosphorylation level 7: regulation of attachment of spindle microtubules to kinetochore level 7: peptidyl-serine phosphorylation level 9: protein localization to kinetochore
GO Terms: Molecular Function	level 3: kinetochore binding level 3: transferase activity level 4: nucleotide binding level 4: protein kinase activity level 5: protein serine/threonine/tyrosine kinase activity level 5: kinase activity level 5: protein serine/threonine kinase activity level 6: ATP binding level 6: MAP kinase kinase activity
GO Terms: Cellular Component	level 4: spindle pole body level 4: kinetochore level 5: nucleus
External source	Open in SGD