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Gene Ontology Information

Protein Name Hem3p
Description Porphobilinogen deaminase; catalyzes the conversion of 4-porphobilinogen to hydroxymethylbilane, the third step in heme biosynthesis; localizes to the cytoplasm and nucleus; expression is regulated by Hap2p-Hap3p, but not by levels of heme; human homolog HMBS can complement yeast mutant and allow growth of haploid null after sporulation of a heterozygous diploid
GO Terms:
Biological Process		 level 5: heme biosynthetic process external link
level 6: protoporphyrinogen IX biosynthetic process external link
level 6: tetrapyrrole biosynthetic process external link
level 7: porphyrin-containing compound biosynthetic process external link
level 8: peptidyl-pyrromethane cofactor linkage external link
GO Terms:
Molecular Function		 level 3: transferase activity external link
level 5: hydroxymethylbilane synthase activity external link
GO Terms:
Cellular Component		 level 3: cytoplasm external link
level 5: nucleus external link
External source Open in SGD external link
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