S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Ycf1p
Description	Vacuolar glutathione S-conjugate transporter; ABC-C transporter of the ATP-binding cassette family; required for vacuole fusion; forms stable complexes with vacuole fusion machinery; regulates Vam7p recruitment to vacuoles; role in detoxifying metals (Cd, Hg, As); transports GSSG that is not immediately reduced in cytosol to vacuole; transports unconjugated bilirubin, selenodigluthatione, oxidized glutathione; similar to human cystic fibrosis protein CFTR
GO Terms: Biological Process	level 3: transmembrane transport level 4: cell redox homeostasis level 5: glutathione metabolic process level 5: response to metal ion level 6: response to cadmium ion level 6: bilirubin transport level 6: peptide transport level 7: cadmium ion transmembrane transport level 8: vacuole fusion, non-autophagic
GO Terms: Molecular Function	level 3: ATPase-coupled transmembrane transporter activity level 4: nucleotide binding level 4: ABC-type transporter activity level 5: ABC-type glutathione S-conjugate transporter activity level 5: ABC-type cadmium transporter activity level 5: ABC-type peptide transporter activity level 6: ATP binding level 7: bilirubin transmembrane transporter activity
GO Terms: Cellular Component	level 3: membrane level 4: vacuole level 4: integral component of membrane level 5: vacuolar membrane level 5: membrane raft level 6: fungal-type vacuole level 7: fungal-type vacuole membrane
External source	Open in SGD