S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Ume6p
Description	Rpd3L histone deacetylase complex subunit; key transcriptional regulator of early meiotic genes; involved in chromatin remodeling and transcriptional repression via DNA looping; binds URS1 upstream regulatory sequence, represses transcription by recruiting conserved histone deacetylase Rpd3p (through co-repressor Sin3p) and chromatin-remodeling factor Isw2p; couples metabolic responses to nutritional cues with initiation and progression of meiosis
GO Terms: Biological Process	level 4: positive regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle level 4: negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle level 4: pseudohyphal growth level 5: spore germination level 5: chromatin organization level 6: lipid droplet organization level 6: chromatin remodeling level 7: regulation of DNA-templated transcription level 8: nitrogen catabolite repression of transcription from RNA polymerase II promoter level 9: positive regulation of transcription by RNA polymerase II level 9: negative regulation of transcription by RNA polymerase II
GO Terms: Molecular Function	level 3: DNA-binding transcription factor activity level 4: DNA-binding transcription factor activity, RNA polymerase II-specific level 5: DNA-binding transcription repressor activity, RNA polymerase II-specific level 5: DNA binding level 5: metal ion binding level 5: DNA-binding transcription factor binding level 6: sequence-specific DNA binding level 6: transcription cis-regulatory region binding level 7: zinc ion binding level 8: RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO Terms: Cellular Component	level 4: Rpd3L-Expanded complex level 5: Rpd3L complex level 5: nucleus
External source	Open in SGD