S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Rad9p
Description	DNA damage-dependent checkpoint protein; required for cell-cycle arrest in G1/S, intra-S, and G2/M, plays a role in postreplication repair (PRR) pathway; transmits checkpoint signal by activating Rad53p and Chk1p; protects double-strand breaks from premature resection; multiple cyclin dependent kinase consensus sites and the C-terminal BRCT domain contribute to DNA damage checkpoint activation; Rad9p Chk1 Activating Domain (CAD) is phosphorylated at multiple sites by Cdc28p/Clb2p
GO Terms: Biological Process	level 3: cell cycle level 4: regulation of catalytic activity level 5: regulation of cell cycle level 5: cellular response to DNA damage stimulus level 6: DNA damage checkpoint signaling level 6: mitotic G1 DNA damage checkpoint signaling level 6: mitotic intra-S DNA damage checkpoint signaling level 6: DNA repair level 7: nucleotide-excision repair level 7: double-strand break repair level 8: negative regulation of DNA strand resection involved in replication fork processing level 8: negative regulation of DNA replication level 9: positive regulation of transcription by RNA polymerase II
GO Terms: Molecular Function	level 4: enzyme activator activity level 4: histone binding level 6: double-stranded DNA binding
GO Terms: Cellular Component	level 3: chromatin level 5: nucleus
External source	Open in SGD