S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Gcn2p
Description	Protein kinase; phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control
GO Terms: Biological Process	level 5: negative regulation of catalytic activity level 5: translation level 6: phosphorylation level 6: DNA damage checkpoint signaling level 6: protein phosphorylation level 6: regulation of translational initiation by eIF2 alpha phosphorylation level 7: negative regulation of protein kinase activity by protein phosphorylation level 7: regulation of translation level 7: positive regulation of cellular response to amino acid starvation level 8: regulation of translational initiation level 9: negative regulation of TORC1 signaling level 9: positive regulation of macroautophagy
GO Terms: Molecular Function	level 3: transferase activity level 3: eukaryotic translation initiation factor 2alpha kinase activity level 4: nucleotide binding level 4: protein kinase activity level 5: RNA binding level 5: protein serine/threonine kinase activity level 5: kinase activity level 6: ATP binding level 6: tRNA binding
GO Terms: Cellular Component	level 3: cytoplasm level 3: cytosol level 4: cytosolic ribosome
External source	Open in SGD