S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Hrq1p
Description	3'-5' DNA helicase of the conserved RecQ family; involved in Pso2p-mediated interstrand crosslink repair; acts with Rad4p in nucleotide-excision repair; binds telomeres, modulates telomerase activity with Pif1p and inhibits telomere addition to dsDNA breaks; role in telomerase-independent telomere maintenance; lacks ssDNA annealing and strand exchange activities; human RecQL4, a structural and functional homolog, is involved in Rothmund-Thomson, Baller-Gerold and RAPADILINO syndromes
GO Terms: Biological Process	level 5: cellular response to DNA damage stimulus level 6: telomere assembly level 6: DNA repair level 7: positive regulation of nuclease activity level 7: regulation of telomere maintenance level 7: interstrand cross-link repair level 7: nucleotide-excision repair level 9: DNA duplex unwinding
GO Terms: Molecular Function	level 3: hydrolase activity level 3: helicase activity level 4: enzyme activator activity level 4: nucleotide binding level 4: nucleic acid binding level 5: DNA binding level 5: 3'-5' DNA helicase activity level 6: single-stranded DNA binding level 6: ATP binding level 7: zinc ion binding level 7: telomeric DNA binding
GO Terms: Cellular Component	level 5: nucleus
External source	Open in SGD