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Gene Ontology Information

Protein Name Swr1p
Description Swi2/Snf2-related ATPase; catalytic subunit of SWR1 complex, which exchanges histone variant H2A.Z (Htz1p) for chromatin-bound histone H2A; N-terminus can deliver H2A.Z-H2B dimer to DNA-(H3-H4)2 tetrasome; relocalizes to cytosol in response to hypoxia; chronological aging factor, mediates lifespan extension by dietary restriction
GO Terms:
Biological Process		 level 5: chromatin organization external link
level 6: chromatin remodeling external link
level 7: recombinational repair external link
level 8: histone exchange external link
GO Terms:
Molecular Function		 level 2: structural molecule activity external link
level 3: hydrolase activity external link
level 3: ATP hydrolysis activity external link
level 3: helicase activity external link
level 4: nucleotide binding external link
level 4: histone binding external link
level 4: ATP-dependent chromatin remodeler activity external link
level 5: DNA binding external link
level 6: ATP binding external link
GO Terms:
Cellular Component		 level 3: cytosol external link
level 5: nucleus external link
level 5: Swr1 complex external link
External source Open in SGD external link
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