S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Nhx1p
Description	Na+/H+ and K+/H+ exchanger; required for intracellular sequestration of Na+ and K+; located in the vacuole and late endosome compartments; required for osmotolerance to acute hypertonic shock and for vacuolar fusion; ortholog of human NHE9, which is linked to autism
GO Terms: Biological Process	level 3: transmembrane transport level 5: ion transport level 6: cation transport level 7: multivesicular body-lysosome fusion level 7: potassium ion transmembrane transport level 7: proton transmembrane transport level 7: cellular monovalent inorganic cation homeostasis level 7: sodium ion transmembrane transport level 8: potassium ion transport level 8: sodium ion transport level 9: regulation of pH level 9: regulation of intracellular pH level 11: vacuolar acidification
GO Terms: Molecular Function	level 6: antiporter activity level 7: solute:proton antiporter activity level 8: sodium:proton antiporter activity level 9: potassium:proton antiporter activity
GO Terms: Cellular Component	level 3: membrane level 4: endosome level 4: endoplasmic reticulum level 4: integral component of membrane level 5: endosome membrane level 5: early endosome level 5: late endosome level 5: trans-Golgi network level 7: fungal-type vacuole membrane
External source	Open in SGD