S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Spf1p
Description	P-type ATPase, ion transporter of the ER membrane; required to maintain normal lipid and sterol composition of intracellular compartments and proper targeting of mitochondrial outer membrane tail-anchored proteins; involved in ER function and Ca2+ homeostasis; required for regulating Hmg2p degradation; confers sensitivity to a killer toxin (SMKT) produced by Pichia farinosa KK1; null mutation is complemented by human Parkinson disease-related ATP13A1
GO Terms: Biological Process	level 3: transmembrane transport level 4: ion transmembrane transport level 5: protein transport level 5: cation transmembrane transport level 6: cation transport level 7: sterol homeostasis level 8: cellular calcium ion homeostasis level 9: cellular manganese ion homeostasis
GO Terms: Molecular Function	level 3: ATP hydrolysis activity level 4: nucleotide binding level 4: P-type transmembrane transporter activity level 4: ATPase-coupled cation transmembrane transporter activity level 5: metal ion binding level 5: P-type ion transporter activity level 6: ATP binding level 7: phosphatidylinositol-4-phosphate binding
GO Terms: Cellular Component	level 3: membrane level 4: integral component of membrane level 4: mitochondrion level 4: endoplasmic reticulum level 5: endoplasmic reticulum membrane level 5: cis-Golgi network level 6: integral component of endoplasmic reticulum membrane
External source	Open in SGD