S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Rad4p
Description	Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2; recognizes and binds damaged DNA with Rad23p during nucleotide excision repair (NER); also involved with Rad23p in turnover of ubiquitylated proteins; Rad4p-Rad23p heterodimer binds to promoters of DNA damage response genes to repress their transcription in the absence of DNA damage; RAD4 and RAD51 pathways confer resistance to benzo[a]pyrene dihydrodiol
GO Terms: Biological Process	level 5: cellular response to DNA damage stimulus level 6: DNA topological change level 6: DNA repair level 7: nucleotide-excision repair level 7: mismatch repair level 7: proteasome-mediated ubiquitin-dependent protein catabolic process level 9: negative regulation of transcription by RNA polymerase II
GO Terms: Molecular Function	level 5: DNA binding level 6: damaged DNA binding level 6: single-stranded DNA binding level 7: single-strand break-containing DNA binding
GO Terms: Cellular Component	level 3: cytosol level 3: cytoplasm level 5: nucleotide-excision repair factor 2 complex level 5: XPC complex level 5: nucleus
External source	Open in SGD