S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Dnf1p
Description	Aminophospholipid translocase (flippase); type 4 P-type ATPase; involved in phospholipid translocation, contributing to endocytosis, protein transport, and cellular polarization; localizes primarily to the plasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; DNF1 has a paralog, DNF2, that arose from the whole genome duplication
GO Terms: Biological Process	level 3: establishment or maintenance of cell polarity level 5: lipid transport level 5: intracellular protein transport level 6: endocytosis level 6: phospholipid transport level 6: phospholipid translocation level 7: ceramide translocation level 7: response to pheromone triggering conjugation with cellular fusion
GO Terms: Molecular Function	level 3: ATPase-coupled intramembrane lipid transporter activity level 3: ATP hydrolysis activity level 4: nucleotide binding level 5: glycosylceramide flippase activity level 6: magnesium ion binding level 6: ATP binding level 6: phosphatidylcholine flippase activity level 6: phosphatidylethanolamine flippase activity
GO Terms: Cellular Component	level 3: membrane level 3: cell periphery level 4: mitochondrion level 4: endosome level 4: phospholipid-translocating ATPase complex level 4: endoplasmic reticulum level 4: integral component of membrane level 4: Golgi apparatus level 4: plasma membrane level 4: cellular bud neck level 5: endosome membrane level 5: mating projection tip membrane
External source	Open in SGD