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Gene Ontology Information

Protein Name Brr2p
Description RNA-dependent ATPase RNA helicase (DEIH box); required for disruption of U4/U6 base-pairing in native snRNPs to activate the spliceosome for catalysis; homologous to human U5-200kD
GO Terms:
Biological Process		 level 7: mRNA processing external link
level 7: RNA splicing external link
level 7: spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) external link
GO Terms:
Molecular Function		 level 3: helicase activity external link
level 3: hydrolase activity external link
level 4: RNA helicase activity external link
level 4: nucleotide binding external link
level 4: nucleic acid binding external link
level 6: ATP binding external link
GO Terms:
Cellular Component		 level 4: spliceosomal complex external link
level 5: nucleus external link
level 6: U5 snRNP external link
level 7: U4/U6 x U5 tri-snRNP complex external link
External source Open in SGD external link
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