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Gene Ontology Information

Protein Name Blm10p
Description Proteasome activator; binds the core proteasome (CP) and stimulates proteasome-mediated protein degradation by inducing gate opening; required for sequestering CP into proteasome storage granule (PSG) during quiescent phase and for nuclear import of CP in proliferating cells; required for resistance to bleomycin, may be involved in protecting against oxidative damage; similar to mammalian PA200
GO Terms:
Biological Process
level 4: proteasome core complex import into nucleus external link
level 5: cellular response to DNA damage stimulus external link
level 6: DNA repair external link
level 7: proteasomal ubiquitin-independent protein catabolic process external link
level 7: positive regulation of peptidase activity external link
level 7: proteasome assembly external link
level 7: regulation of proteasomal protein catabolic process external link
level 8: proteasome storage granule assembly external link
GO Terms:
Molecular Function
level 4: proteasome binding external link
level 5: peptidase activator activity external link
level 5: lysine-acetylated histone binding external link
GO Terms:
Cellular Component
level 3: cytoplasm external link
level 3: cytosol external link
level 4: proteasome storage granule external link
level 5: nucleus external link
External source Open in SGD external link
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