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manipulating TF expression
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Gene Ontology Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Protein Name
Pmc1p
Description
Vacuolar Ca2+ ATPase involved in depleting cytosol of Ca2+ ions; prevents growth inhibition by activation of calcineurin in the presence of elevated concentrations of calcium; similar to mammalian PMCA1a
GO Terms:
Biological Process
level 3:
transmembrane transport
level 5:
ion transport
level 7:
calcium ion transmembrane transport
level 8:
calcium ion transport
level 8:
cellular calcium ion homeostasis
GO Terms:
Molecular Function
level 3:
ATP hydrolysis activity
level 4:
nucleotide binding
level 4:
ATPase-coupled cation transmembrane transporter activity
level 5:
metal ion binding
level 5:
P-type calcium transporter activity
level 6:
ATP binding
GO Terms:
Cellular Component
level 3:
membrane
level 4:
integral component of membrane
level 4:
intracellular membrane-bounded organelle
level 4:
vacuole
level 5:
vacuolar membrane
level 5:
integral component of plasma membrane
level 7:
fungal-type vacuole membrane
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