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Gene Ontology Information

Protein Name Ime4p
Description mRNA N6-adenosine methyltransferase essential for meiosis in S288C but dispensable for meiosis in SK1; mediates N6-adenosine methylation of bulk mRNA during the induction of sporulation which includes the meiotic regulators IME1, IME2 and IME4 itself; repressed in haploids via production of antisense IME4 transcripts; transcribed in diploid cells where antisense transcription is repressed; orthologous to human METTL3 (MT-A70)
GO Terms:
Biological Process
level 3: meiotic cell cycle external link
level 3: methylation external link
level 4: meiotic DNA replication initiation external link
level 4: sporulation resulting in formation of a cellular spore external link
level 6: mRNA methylation external link
level 7: negative regulation of pseudohyphal growth external link
GO Terms:
Molecular Function
level 3: transferase activity external link
level 5: RNA binding external link
level 5: methyltransferase activity external link
level 7: mRNA (N6-adenosine)-methyltransferase activity external link
GO Terms:
Cellular Component
level 3: cytoplasm external link
level 5: RNA N6-methyladenosine methyltransferase complex external link
level 5: nucleus external link
level 5: nucleolus external link
External source Open in SGD external link
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