S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Erv1p
Description	Flavin-linked sulfhydryl oxidase of the mitochondrial IMS; N-terminus is an intrinsically disordered domain that in the cytosol helps target Erv1p to mitochondria, and in the intermembrane space oxidizes Mia40p as part of a disulfide relay system that promotes intermembrane space retention of imported proteins; functional ortholog of human GFER (ALR); human GFER carrying N-terminal 21 amino acids of Erv1p functionally complements the lethality of the erv1 null mutation
GO Terms: Biological Process	level 5: cellular response to oxidative stress level 5: protein import into mitochondrial intermembrane space level 9: cellular iron ion homeostasis
GO Terms: Molecular Function	level 3: oxidoreductase activity level 5: flavin-linked sulfhydryl oxidase activity level 5: flavin adenine dinucleotide binding level 6: thiol oxidase activity
GO Terms: Cellular Component	level 4: mitochondrion level 6: mitochondrial intermembrane space
External source	Open in SGD