S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Coq6p
Description	Flavin-dependent monooxygenase involved in ubiquinone biosynthesis; responsible for hydroxylation at position C5 and deamination at C4 during ubiquinone (Coenzyme Q) biosynthesis; localizes to matrix face of mitochondrial inner membrane in a large complex with other ubiquinone biosynthetic enzymes; human homolog COQ6 can complement yeast null mutant and is implicated in steroid-resistant nephrotic syndrome (SRNS)
GO Terms: Biological Process	level 7: ubiquinone biosynthetic process
GO Terms: Molecular Function	level 3: oxidoreductase activity level 3: hydrolase activity level 4: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen level 4: monooxygenase activity level 5: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen level 5: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen level 5: flavin adenine dinucleotide binding level 5: 2-octaprenyl-6-methoxyphenol hydroxylase activity level 6: FAD binding
GO Terms: Cellular Component	level 3: membrane level 4: mitochondrion level 5: extrinsic component of mitochondrial inner membrane level 6: mitochondrial inner membrane
External source	Open in SGD