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Gene Ontology Information

Protein Name Mad3p
Description Subunit of spindle-assembly checkpoint complex; involved in delaying anaphase onset in cells with defects in mitotic spindle assembly; pseudosubstrate inhibitor of APC(Cdc20), the anaphase promoting complex involved in securin (Pds1p) turnover; MAD3 has a paralog, BUB1, that arose from the whole genome duplication
GO Terms:
Biological Process		 level 3: cell cycle external link
level 3: cell division external link
level 5: mitotic spindle assembly checkpoint signaling external link
level 5: distributive segregation external link
level 5: mitotic DNA integrity checkpoint signaling external link
level 6: meiotic sister chromatid cohesion, centromeric external link
level 11: positive regulation of protein autoubiquitination external link
GO Terms:
Molecular Function		 level 1: molecular_function external link
level 4: protein kinase activity external link
GO Terms:
Cellular Component		 level 4: mitotic checkpoint complex external link
level 5: nucleus external link
External source Open in SGD external link
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