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Gene Ontology Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Protein Name
Phs1p
Description
Essential 3-hydroxyacyl-CoA dehydratase of the ER membrane; involved in elongation of very long-chain fatty acids; evolutionarily conserved, similar to mammalian PTPLA and PTPLB; involved in sphingolipid biosynthesis and protein trafficking
GO Terms:
Biological Process
level 4:
lipid metabolic process
level 5:
fatty acid metabolic process
level 5:
vacuolar transport
level 6:
sphingolipid biosynthetic process
level 6:
fatty acid biosynthetic process
level 7:
fatty acid elongation
level 7:
very long-chain fatty acid biosynthetic process
GO Terms:
Molecular Function
level 3:
lyase activity
level 6:
3-hydroxy-lignoceroyl-CoA dehydratase activity
level 6:
enoyl-CoA hydratase activity
level 6:
3-hydroxyacyl-CoA dehydratase activity
level 6:
very-long-chain 3-hydroxyacyl-CoA dehydratase activity
level 6:
3-hydroxy-arachidoyl-CoA dehydratase activity
level 6:
3-hydroxy-behenoyl-CoA dehydratase activity
GO Terms:
Cellular Component
level 3:
membrane
level 4:
integral component of membrane
level 4:
vacuole
level 4:
endoplasmic reticulum
level 4:
nuclear outer membrane-endoplasmic reticulum membrane network
level 5:
vacuolar membrane
level 5:
endoplasmic reticulum membrane
level 6:
integral component of endoplasmic reticulum membrane
level 6:
fungal-type vacuole
level 7:
fungal-type vacuole membrane
External source
Open in SGD