S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Nfu1p
Description	Protein involved in Fe-S cluster transfer to mitochondrial clients; protects [4Fe-4S] clusters from damage due to oxidative stress; acts along with Bol3 at a late step in the transfer of [4Fe-4S] clusters from the ISA complex to client proteins; Fe-S loaded homodimer at steady state; similar to NifU, a bacterial protein required for Fe/S cluster maturation; ortholog of the human NFU1, mutations of which are associated with Multiple Mitochondria Dysfunctions Syndrome (MMDS1)
GO Terms: Biological Process	level 5: intracellular sequestering of iron ion level 5: iron-sulfur cluster assembly level 6: protein maturation by iron-sulfur cluster transfer level 7: protein maturation by [4Fe-4S] cluster transfer
GO Terms: Molecular Function	level 1: molecular_function level 4: iron-sulfur cluster binding level 5: 4 iron, 4 sulfur cluster binding level 7: iron ion binding
GO Terms: Cellular Component	level 4: mitochondrion level 5: mitochondrial matrix
External source	Open in SGD