S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Ypk1p
Description	S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant and the inviability of a ypk1 ypk2 double mutant
GO Terms: Biological Process	level 4: cell wall organization level 4: intracellular signal transduction level 4: regulation of catalytic activity level 6: glycerophospholipid metabolic process level 6: eisosome assembly level 6: endocytosis level 6: cellular response to acetate level 6: phosphorylation level 6: regulation of fungal-type cell wall organization level 6: protein phosphorylation level 6: negative regulation of phospholipid translocation level 7: response to pheromone triggering conjugation with cellular fusion level 7: negative regulation of sphingolipid biosynthetic process level 7: peptidyl-serine phosphorylation
GO Terms: Molecular Function	level 3: transferase activity level 4: nucleotide binding level 4: protein kinase activity level 5: kinase activity level 5: protein serine/threonine kinase activity level 6: ATP binding
GO Terms: Cellular Component	level 3: membrane level 3: cytoplasm level 3: cytosol level 4: plasma membrane level 4: cellular bud neck
External source	Open in SGD