S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Doa1p
Description	WD-repeat protein involved in ubiquitin-mediated protein degradation; Ub-binding protein with a role in Ub homeostasis; substrate-recruiting adaptor for Cdc48p in mitochondria-associated degradation; inhibits degradation of Ufd2p-dependent substrates; facilitates proteolysis of Cse4p, a centromeric H3-like protein; required for ribophagy; promotes NHEJ in postdiauxic/stationary phase; protein increases in abundance and relocalizes from nucleus to nuclear periphery upon DNA replication stress
GO Terms: Biological Process	level 4: ubiquitin recycling level 7: ribophagy level 7: proteasome-mediated ubiquitin-dependent protein catabolic process level 8: mitochondria-associated ubiquitin-dependent protein catabolic process level 8: double-strand break repair via nonhomologous end joining
GO Terms: Molecular Function	level 5: ubiquitin binding level 6: K48-linked polyubiquitin modification-dependent protein binding
GO Terms: Cellular Component	level 3: membrane level 3: cytoplasm level 4: endosome level 4: mitochondrion level 5: endosome membrane level 5: nucleus level 6: mitochondrial outer membrane
External source	Open in SGD