Yeastract
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Gene Ontology Information

Protein Name Las1p
Description Endonuclease involved in pre-rRNA processing at both ends of ITS2; functions with Grc3p in a conserved mechanism to cleave pre-rRNA at a specific site during rRNA processing and ribosome biogenesis; may coordinate the action of the Rat1p-Rai1p exoRNAse; required for the G1/S cell cycle transition; human ortholog is Las1L; mutants require the SSD1-v allele for viability
GO Terms:
Biological Process
level 7: maturation of LSU-rRNA external link
level 7: rRNA processing external link
level 8: maturation of 5.8S rRNA external link
level 9: cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) external link
GO Terms:
Molecular Function
level 6: endonuclease activity external link
GO Terms:
Cellular Component
level 3: cytoplasm external link
level 4: Las1 complex external link
level 4: mitochondrion external link
level 5: preribosome, large subunit precursor external link
level 5: nucleus external link
level 5: nucleolus external link
External source Open in SGD external link
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