S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Sis2p
Description	Negative regulatory subunit of protein phosphatase 1 (Ppz1p); involved in coenzyme A biosynthesis; subunit of phosphopantothenoylcysteine decarboxylase (PPCDC: Cab3p, Sis2p, Vhs3p) complex and the CoA-Synthesizing Protein Complex (CoA-SPC: Cab2p, Cab3p, Cab4p, Cab5p, Sis2p and Vhs3p); SIS2 has a paralog, VHS3, that arose from the whole genome duplication
GO Terms: Biological Process	level 5: response to salt stress level 6: regulation of mitotic cell cycle level 8: coenzyme A biosynthetic process level 8: negative regulation of phosphoprotein phosphatase activity
GO Terms: Molecular Function	level 2: catalytic activity level 5: FMN binding level 6: protein phosphatase inhibitor activity level 6: phosphopantothenoylcysteine decarboxylase activity level 7: protein serine/threonine phosphatase inhibitor activity
GO Terms: Cellular Component	level 3: cytoplasm level 3: chromatin level 4: CoA-synthesizing protein complex level 4: phosphopantothenoylcysteine decarboxylase complex level 5: nucleus
External source	Open in SGD