S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Erg3p
Description	C-5 sterol desaturase; glycoprotein that catalyzes the introduction of a C-5(6) double bond into episterol, a precursor in ergosterol biosynthesis; transcriptionally down-regulated when ergosterol is in excess; mutants are viable, but cannot grow on non-fermentable carbon sources; substrate of HRD ubiquitin ligase; mutation is functionally complemented by human SC5D
GO Terms: Biological Process	level 4: lipid metabolic process level 5: steroid metabolic process level 5: lipid biosynthetic process level 6: ergosterol biosynthetic process level 6: sterol biosynthetic process level 6: steroid biosynthetic process
GO Terms: Molecular Function	level 3: oxidoreductase activity level 6: C-5 sterol desaturase activity level 6: delta7-sterol 5(6)-desaturase activity level 7: iron ion binding
GO Terms: Cellular Component	level 3: membrane level 4: integral component of membrane level 4: endoplasmic reticulum level 5: endoplasmic reticulum lumen level 5: endoplasmic reticulum membrane
External source	Open in SGD