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Modelling prediction
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[metab] Optimisation
manipulating gene expression
manipulating TF expression
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Gene Ontology Information
Locus Info
Protein Info
GO Info
Orthologs
Protein Name
Hrd3p
Description
ER membrane protein that plays a central role in ERAD; forms HRD complex with Hrd1p and ER-associated protein degradation (ERAD) determinants that engages in lumen to cytosol communication and coordination of ERAD events
GO Terms:
Biological Process
level 6:
ERAD pathway
level 6:
retrograde protein transport, ER to cytosol
level 7:
ubiquitin-dependent ERAD pathway
level 8:
protein ubiquitination
level 11:
negative regulation of protein autoubiquitination
GO Terms:
Molecular Function
level 5:
ubiquitin-protein transferase activity
GO Terms:
Cellular Component
level 3:
membrane
level 4:
luminal surveillance complex
level 4:
endoplasmic reticulum
level 4:
integral component of membrane
level 5:
endoplasmic reticulum membrane
level 6:
Hrd1p ubiquitin ligase ERAD-M complex
level 6:
Hrd1p ubiquitin ligase ERAD-L complex
External source
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