S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Cdc25p
Description	Membrane bound guanine nucleotide exchange factor; also known as a GEF or GDP-release factor; indirectly regulates adenylate cyclase through activation of Ras1p and Ras2p by stimulating the exchange of GDP for GTP; required for progression through G1; thermosensitivity of the cdc25-5 mutant is functionally complemented by human RASGRF1 or by a fragment of human SOS1 comprising the CDC25-related catalytic domain
GO Terms: Biological Process	level 3: cell cycle level 3: cell division level 5: regulation of cell cycle level 5: small GTPase mediated signal transduction level 6: Ras protein signal transduction level 7: positive regulation of GTPase activity level 10: traversing start control point of mitotic cell cycle
GO Terms: Molecular Function	level 6: guanyl-nucleotide exchange factor activity
GO Terms: Cellular Component	level 3: cytosol level 3: membrane level 3: cytoplasm level 4: plasma membrane level 4: integral component of membrane level 5: endoplasmic reticulum membrane level 5: nucleus
External source	Open in SGD