S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Bud6p
Description	Actin- and formin-interacting protein; nucleation-promoting factor (NPF) for Bni1p and Bnr1p during actin cable assembly and organization; enhances Bnr1p-mediated actin nucleation, alleviating Hof1p inhibition through competitive binding; interacts with Bni1p via a C-terminal triple helical coiled-coil domain; role in polarized cell growth; isolated as a bipolar budding mutant; localizes to the presumptive bud site, small bud tips, the bud neck and secretory vesicles; potential Cdc28p substrate
GO Terms: Biological Process	level 4: establishment of cell polarity level 4: regulation of catalytic activity level 4: budding cell apical bud growth level 4: pseudohyphal growth level 5: astral microtubule organization level 5: bipolar cellular bud site selection level 6: regulation of protein localization level 6: actin filament bundle assembly level 8: positive regulation of actin cytoskeleton reorganization level 8: regulation of actin nucleation level 8: positive regulation of actin nucleation level 8: positive regulation of formin-nucleated actin cable assembly
GO Terms: Molecular Function	level 4: enzyme activator activity level 5: actin binding level 5: cytoskeletal regulatory protein binding
GO Terms: Cellular Component	level 3: cytoplasm level 3: polarisome level 4: prospore membrane level 4: mating projection tip level 4: spindle pole body level 4: cellular bud tip level 4: cellular bud neck level 4: cell tip level 4: incipient cellular bud site level 5: secretory vesicle
External source	Open in SGD