S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Orm2p
Description	Protein that mediates sphingolipid homeostasis; evolutionarily conserved, required for resistance to agents that induce unfolded protein response; Orm1p and Orm2p together control membrane biogenesis by coordinating lipid homeostasis with protein quality control; protein abundance increases in response to DNA replication stress; ORM2 has a paralog, ORM1, that arose from the whole genome duplication
GO Terms: Biological Process	level 5: response to unfolded protein level 5: cellular sphingolipid homeostasis level 6: ceramide metabolic process level 7: negative regulation of sphingolipid biosynthetic process level 8: negative regulation of ceramide biosynthetic process
GO Terms: Molecular Function	level 1: molecular_function
GO Terms: Cellular Component	level 3: membrane level 4: integral component of membrane level 4: endoplasmic reticulum level 5: endoplasmic reticulum membrane level 6: SPOTS complex
External source	Open in SGD